Gene Therapies

Most genetic research has focused people of European descent. Some are fighting to bring discarded data from other groups back to the table.

Some people are born deaf; others lose hearing because of injury or as they age. New approaches could open their ears.

Re-engineered cells are making waves in cancer treatment. But there may be a safer way to achieve the same effect.

The concept of circuitry, borrowed from computer technology, could make the next generation of gene therapies more flexible and powerful.

Genetic tests and genome sequencing are generating terabytes of sensitive private data. How can they be kept safe?

“Large molecule” therapies, tailored to home in on otherwise untreatable ills, have become medicine’s hottest commodity.

Zinc fingers could pull gene therapy back from the brink—but only if more researchers can get their hands on the remarkable proteins.

Top Stories

The final illness of the physician and author happens 100 years after the greatest outbreak of encephalitis lethargica.

They represent a small minority of victims. But their illness could hold valuable lessons about how COVID-19 works—and how to stop it.

After 50 years, we take a look back at the pharmaceutical industry’s first $100 million brand.

Selected Reads

For decades, a tiny encampment of researchers has held that statin treatment is a hoax. In a time when contrarian views roar to life on social media, how can medicine keep minority opinions from doing irreparable harm?

Two years in deep space will subject the body to unprecedented stresses. Scientists are probing the secrets to survival.

A freak explosion tore through the quiet Nova Scotian city, prompting one of the most dramatic medical responses in history.