Pathology

Receptors that can smell and taste exist throughout the body. Can they be allies in learning to fight disease?

Could Parkinson’s disease, a brain disorder, have its origin somewhere else? A controversial theory is gaining ground.

Miniature versions of organs help scientists understand disease and fine-tune treatments in ways that work in mice can’t match.

The 50-year crusade to prove the link between viruses and cancer

In most cases, antibiotics do the trick. But when they don’t, symptoms can be devastating. New research aims to discover why.

Trouble with the protein may underlie most kinds of dementia, potentially including Alzheimer’s. New drugs could help.

A century ago, MGH pathologist Richard Cabot made an event out of physicians identifying illnesses—and greatly improved diagnostic methods as a result.

If, as some scientists suspect, illnesses that strike late in life have a common root, similar therapies might help us avoid many of them.

What causes osteoarthritis? Not wear and tear, apparently, but bone lesions, misaligned joints and fat-cell-generated inflammation.

New research sheds light on the mystery of prions: misfolded proteins that promote a lethal chain of events.

Kuru, scrapie, a fatal form of insomnia—all caused by renegade proteins. Cure one and other, more familiar diseases may follow.

Top Stories

In 1922 the Berlin woman became the first to undergo gender-affirming surgery.

A century ago, chemist Søren Sørensen invented what would become a crucial diagnostic tool: the pH scale.

A novel coronavirus would come to affect every ward, clinician, researcher and patient at Massachusetts General Hospital.

Selected Reads

For decades, a tiny encampment of researchers has held that statin treatment is a hoax. In a time when contrarian views roar to life on social media, how can medicine keep minority opinions from doing irreparable harm?

Two years in deep space will subject the body to unprecedented stresses. Scientists are probing the secrets to survival.

A freak explosion tore through the quiet Nova Scotian city, prompting one of the most dramatic medical responses in history.