A surge of research into psilocybin, LSD and other psychedelic drugs, all still illegal, seeks to identify the mechanisms behind the compounds’ extraordinary effectiveness in treating many mental illnesses. Also in this issue: Health care’s staffing crisis is deep and wide, prompting innovative efforts to convince workers to stay. Plus, new approaches look to break the link between childhood adversity and adult health problems. And a team effort to treat a child’s acute diarrhea leads to the discovery of a rare disease.