Infectious Disease

Syphilis brought the very first patient to the hospital—and the disease drove some of the most important moments in medicine.

Genetically engineered microbes could create miniature drug factories inside the gut. Do the benefits outweigh the risks?

Mini gut models give scientists a front row seat to some of the most puzzling pathogen behaviors.

A milestone vaccine will soon move forward in clinical trials. But does its target—the MAP bacterium—actually play a role in the condition?

At least 10% of cancers are probably caused by a viral infection. But researchers struggle to replicate the success they have had with cervical cancer.

Vaccine skepticism is a growing problem in the Muslim world, too. Making medicines without pork products is one obvious—but tricky—solution.

The drug-resistant Candida auris has taken up residence in U.S. hospitals. What will it take to fight back?

Waiting a decade or more for new vaccines may be a thing of the past, thanks to the revolution of rational vaccine design.

Experts comment on the state of HIV/AIDS research and emerging strategies to mitigate the risks of human spaceflight.

As more bacteria gain resistance to standard treatments, is the answer a return to therapeutic metals?

Since the early 1980s, AIDS has killed more than 35 million people worldwide. But researchers are determined to find better treatments, cures and preventions that many finally put an end to the epidemic.

AIDS still kills, in numbers more vast than most people realize. But the right blend of science and policy could end the scourge.

Top Stories

Genomic analysis details how SARS-CoV-2 spread through Boston.

They represent a small minority of victims. But their illness could hold valuable lessons about how COVID-19 works—and how to stop it.

A pristine record of toxic exposures and psychological trauma rests in a child’s mouth—if only it can be decoded.

Selected Reads

For decades, a tiny encampment of researchers has held that statin treatment is a hoax. In a time when contrarian views roar to life on social media, how can medicine keep minority opinions from doing irreparable harm?

Two years in deep space will subject the body to unprecedented stresses. Scientists are probing the secrets to survival.

A freak explosion tore through the quiet Nova Scotian city, prompting one of the most dramatic medical responses in history.