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Prohibition at 100

The 18th Amendment launched the most sweeping health experiment in U.S. history. Physicians—then and now—have debated its complex legacy.

Howard Atwood Kelly, one of the “big four” physicians who founded Johns Hopkins Hospital in Baltimore, held a view of alcohol typical of his generation. He began his career prescribing it to treat weakness, fevers and other conditions. But he found that “the effect is temporary, evanescent, that the drug (for such it is) does no real good,” he said...

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