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What a Hospital is Built For

As COVID-19 first swept through Boston, the people of Massachusetts General Hospital responded. Their efforts offer a portrait of medicine in motion.

Our Response to a Pandemic

Peter L. Slavin and Timothy G. Ferris discuss how Massachusetts General Hospital is tackling COVID-19.

The Changing Landscape of Primary Care

Peter L. Slavin and Timothy G. Ferris discuss a shortage of primary care physicians and how to address the problem.

A Safe and Controversial Place

Physician Mark Eisenberg discusses the furor over (and the desperate need for) safer injection sites.

Next-Generation Vaccines

Peter L. Slavin and Timothy G. Ferris discuss the revolution of rational vaccine design.

A Revolution in Cancer Treatment

Peter L. Slavin and Timothy G. Ferris discuss the promise of CAR T cell therapy for solid tumors.

Climate Change Meets an Aging Population

The most common victims of extreme weather events are older people. New research looks into how the health system fails them, and how it can be fixed.

Singular Exceptions

Should primary care physicians be trained to spot unusual, medically important cases?

Silent No More

Peter L. Slavin and Timothy G. Ferris discuss the need to end workplace violence in health care.

An Extra Pair of (A)Is

Machine intelligence takes a big step into the clinic, with a technology that helps identify patients with an elevated risk of breast cancer.

Doctoring on a Screen

Telemedicine made its first broadcast 50 years ago in an airport clinic.

Ending the AIDS Epidemic

Since the early 1980s, AIDS has killed more than 35 million people worldwide. But researchers are determined to find better treatments, cures and preventions that many finally put an end to the epidemic. 

For Some Clots, It Takes a Village

Treatment of pulmonary embolisms may benefit from a team approach. But that model faces obstacles inside and outside the hospital.

Shining a Light on Depression

Peter L. Slavin and Timothy G. Ferris highlight the need for new approaches to treating depression. 

A (Small) Cause of Big Pain

Neurologist Anne Louise Oaklander investigates a cause of chronic pain that is treatable without opioids.

Investing in Our Future

Peter L. Slavin and Timothy G. Ferris discuss the importance of research funding.

After the Storm

Hurricane Maria shut down a factory where intravenous fluid bags were made. Why has this roiled a nation’s hospital system?

The Crisis in the Air

Slowing climate change is important for our health long term. But cleaning up polluted skies will also yield immediate health benefits.

Medicine in the Mix

The science of embedding medications in polymers opens new doors.

Sparkling Like (Nano) Diamonds

Tiny diamonds set loose in the body can promote a sharper MRI image.  

Respect for Our Elders

Peter L. Slavin discusses the importance of giving older inpatients the proper care. 

The Brain’s Beat

By studying the mysteries of anesthesia and how it affects the brain, Patrick Purdon may have found a new way to predict Alzheimer's disease and other neurodegenerative conditions. 

Untangling Chromatin

More than marvels of biological architecture, structures within the cell nucleus may be intertwined with aging itself.

Marching for Science

Peter L. Slavin discusses why funding research is key to America's future.

A Dream Deferred

Atheendar Venkataramani explores the detrimental effects that immigration policy can have on the mental health of undocumented immigrants.

Where Lost Diseases Go

A new, nationwide team of experts gives the toughest medical cases a chance at a breakthrough.

Second Chances

The Food and Drug Administration tries a fresh approach to medical devices suspected of falling short.

Still Restless

Restless legs syndrome continues to puzzle, even with the recent publication of the first clinical guidelines for the disease.

Hope in the Face of Addiction

Peter L. Slavin and Thomas J. Lynch Jr. discuss the hospital’s responsibility in treating opioid addiction.

The Data Revolution

Peter L. Slavin & Thomas J. Lynch Jr. discuss the growing "open data" movement and its implications for scientific research

A Nudge for Neurology Drugs

New therapies for stroke, multiple sclerosis and other conditions may get a boost from interhospital cooperation.

Clinicians and Social Responsibility

Peter L. Slavin and Thomas J. Lynch Jr. discuss the role of clinicians in promoting health beyond the hospital.

The Big (Data) Picture

Medical images are the next frontier for the data revolution, and a new research center plans on taking a closer look.

Medical Theater

An artist and physician team up to examine the role of acting in the clinical setting

Treating Black Lives

The health care system still delivers poorer care, on average, to African American patients. What can be done?

Lightning in a Bottle

Although nitric oxide helps relieve certain lung conditions, it is expensive and cumbersome to use. A new invention produces the substance from thin air.

The Digital Hospital

Peter L. Slavin and Thomas J. Lynch Jr. weigh in on the promise and challenge of adopting new technologies in hospitals.

A Flu Scare, 10 Years Later

Infectious disease specialist Martin Hirsch looks at the worry over H5N1 and its aftermath.

Turning a Corner in Stroke Care

Neurologist Lee Schwamm looks at 10 pivotal years in the treatment of stroke victims.

A Decade of Palliative Care

The first issue of Proto looked at comfort care for those with grave illnesses. The field of palliative care has since grown by leaps and bounds.

The Pill That Lasts and Lasts

Most patients don’t take their daily medications every day. The technology behind a once-a-month pill could save them from themselves.

Progress on Pig’s Organs

The first issue of Proto looked at the promise of transplanting organs from other species. What’s happened since then?

A Decade of Psychogenetics

The first issue of Proto looked at the genetic roots of mental illness. What’s happened since then?

A Troubling Gap

MGH president Peter Slavin discusses racial disparities at the annual meeting of the Association of American Medical Colleges.

The Codman Affair

Ernest Amory Codman, a pioneer in medical quality assessment, made his stand with a cartoon in 1915. It did not end well.

Scientific Uncertainty

Nobel laureate Jack Szostak reflects on the future of science in the United States.

Keeping the Lights On

Scientific funding has hit a long rough patch. The director of the MGH Research Institute explores alternative ways to provide sustainable and rewarding careers for the next generation of scientists.

How a Disaster Mends

Three months after the last major earthquake in Nepal, two emergency responders from MGH describe the practicalities of delivering care in a disaster zone.

Marginal Care

In this video, MGH oncologist Karen Winkfield illuminates the past, present, and future of U.S. health disparities

Living to Tell the Tale

In this video, Mass General physician Suzanne Koven discusses the power of personal stories inspired by illness.

Taming the Electronic Medical Record

The QPID system uses artificial intelligence to wade through chart data, helping doctors diagnose and treat patients.

Second Opinion? Ask a Computer

Edward Hoffer explains the revolution that DXplain helped to build.

Is There Still Room for Gluten?

In this video, MGH researcher Alessio Fasano distills fact from fiction in the gluten wars.

After the Ice Buckets

Facebook made sure that the world knew about ALS. Now what?

Better Care for the Most Vulnerable

MGH tests new waters with its pioneer program for “complex” patients.

The Tragedy that Powers Still Alice

The Oscar-nominated film puts Alzheimer’s front and center. An MGH social worker talks about the disease behind the story.

What the Pill Sees

A new micro-imaging “pill” lets doctors peer inside the esophagus and beyond.

Foreign Wars, Domestic Tragedies

Families of returning veterans sometimes develop mental health problems of their own. An MGH team studies the problem and looks for solutions.

New Allies in the HIV Fight

An MGH program in South Africa partners with young women to research the earliest phase of HIV infection.

The Warren Triennial Prize Goes to…

The storied award from MGH goes to a molecular biologist breaking new ground in cancer genetics.

Cancer: Take Two Aspirin

The connection between aspirin use and a reduced risk for certain cancers is becoming clearer. MGH researcher Andrew Chan outlines who stands to benefit most.

On the Origin of Life

Nobel Laureate Jack Szostak discusses how research on chromosomes led to current investigations into Earth's first organisms.

The Same As Being There

MGH’s pioneering telestroke network brings virtual consultations to outlying hospitals

A Call for Replication

Peter L. Slavin and David F. Torchiana on the value of reproducing research.

Joint Replacement: Forming Stronger Bonds

Orhun Muratoglu, a physicist in MGH's Harris Orthopaedic Laboratory, explains his group's breakthrough in making prosthetic joints more durable. 

The Legacy of Ward 4

MGH’s clinical research center, opened in 1925, created a model for the NIH to open similar facilities across the country.